ncRNA name | hsa-let-7c |
ncRNA Category | miRNA |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB samples; RB cell line Y79 and WERI-RB1; breast cancer cell lines MDA-MB-453 and MCF-7; human retinal Müller glial cell line MIO-M1; human thyroid follicular epithelial cell line Nthy-ori 3-1 |
Methods | qRT-PCR |
Expression pattern | down-regulated |
Functional description | let-7c and let-7d were highly down regulated in Y79 and WERI-RB1 respectively, when compared to the MIO-M1cell line. |
PubMed ID | 24391761 |
Year | 2013 |
Title | Targeted expression of suicide gene by tissue-specific promoter and microRNA regulation for cancer gene therapy. |
Drug-related ncRNA | NO |
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